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Clinical Presentation

• Unilateral granulomatous conjunctivitis with follicles and swelling of the submandibular and preauricular lymph nodes, accompanied by a general feeling of illness, possibly chronic fever
• Usually excellent prognosis

Causes

• Various infectious diseases; most commonly cat scratch disease (Bartonella henselae), tularemia, syphilis, tuberculosis, leprosy, chlamydia
  • Serological testing

Treatment

• For Bartonella, antibiotic therapy is controversial
  • Consider Azithromycin 10mg/kg body weight once daily for 5 days (maximum daily dose 500mg)
• Infectious disease consultation recommended

Sources

• EyeWiki Parinaud Oculoglandular Syndrome
• The Wills Eye Manual: Office and Emergency Room Diagnosis and Treatment of Eye Disease; Nika Bagheri MD, Brynn Wajda MD, et al; Lippincott Williams&Wilkins; 7th Edition (2016)
• Kanski’s Clinical Ophthalmology: A Systematic Approach; Jack J. Kanski MD, Brad Bowling MD; Saunders Ltd.; 8th Edition (2015)