Contact Lens associated Keratitis

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  • Bacteria: Pseudomonas , Staphylococcus aureus, Streptococci (S. pyogenes, S. pneumoniae)
  • Acanthamoeba
  • Fungi: Candida, Fusarium, Aspergillus


  • Photodocumentation
  • Specimen collection for:
    • Infiltrate >1mm or involving the central visual axis or no response to initial therapy
    • For non-central infiltrate <1mm: Swab not mandatory, low likelihood of pathogen detection
    • Optimal: Direct examination, culture for bacteria + fungi, +/- viral PCR (HSV, VZV)
  • Consider sending in contact lens case including contact lens to microbiology
    • Especially if Acanthamoeba is suspected, otherwise not very helpful as cases are often contaminated



  • daily until improvement
  • Cave: Avoid contact lens use until fully healed (preferably 1 week longer after therapy cessation)


  • EyeWiki Contact lens complications
  • The Wills Eye Manual: Office and Emergency Room Diagnosis and Treatment of Eye Disease; Nika Bagheri MD, Brynn Wajda MD, et al; Lippincott Williams&Wilkins; 7th Edition (2016)
  • Kanski’s Clinical Ophthalmology: A Systematic Approach; Jack J. Kanski MD, Brad Bowling MD; Saunders Ltd.; 8th Edition (2015)
  • 1 Foto: Seraina Tscharner